Domenico Natale Sarro, also Sarri (24 December 1679 – 25 January 1744) was an Italian composer.
He studied at the Neapolitan conservatory of S. Onofrio. He composed extensively in the early 18th century. His opera Didone abbandonata, premiered on 1 February 1724 at the Teatro San Bartolomeo in Naples, was the first setting of a major libretto by Pietro Metastasio. He is best remembered today as the composer of Achille in Sciro, the opera that was chosen to open the new Teatro di San Carlo in 1737.